Show this safety data sheet to the doctor in attendance. Armarego, in purification of laboratory chemicals eighth edition, 2017. We also stock sodium borohydride, please click on the image below for. Sodium hydride cas no 7646697 material safety data sheet sds msds. This material is considered hazardous by the osha hazard. Sodium tetrahydridoborate, sodium tetrahydroborate, sodium boranuide for the msds sds, please click on the pdf logo below opens in a new window. Sodium borohydride nabh4 is a reagent that transforms aldehydes and ketones to the corresponding alcohol, primary or secondary, respectively. Used as a selective reductant which can be used in aqueous solution. Sodium borohydride is also used to reduce aldehydes and ketones in the production of pharmaceuticals including chloramphenicol, thiophenicol, vitamin a, atropine, and scopolamine, as well as many.
The main use is for the reduction of sulfur dioxide to give sodium dithionite. Find msds or sds, a coa, data sheets and more information. Industry applications producers of sodium borohydride and. Sodium hydroxide safety data sheet according to federal register vol. Reason for citation potassium borohydride is on the. The number of electrons in each of potassium s shells is 2, 8, 8, 1 and its electron configuration is ar 4s 1. Potassium borohydride un1870 dangerous when wet ks00000wjf. When exposed to water it may react violently and start a fire. Preparation of potassium borohydride by a mechanochemical reaction of saline hydrides with dehydrated borate through ball milling. It is decomposed by water to form sodium hydroxide, a corrosive. Hazards identification potential acute health effects.
For sampling and testing purposes, utilize polyethylene bottles. Persistence and degradability sodium phosphate, dibasic, anhydrous 7558 79 4 persistence and degradability not established. Application nanocrystalline superlattices in gold colloid solution have been prepared by ligandinduction using aucl 3 reduced with sodium borohydride. It converts aldehydes and ketones to the corresponding alcohols in the manufacture of pharmaceuticals and other fine chemicals. Other articles where sodium tetrahydridoborate is discussed. Xray diffraction xrd analysis showed the presence of fe 3 o 4. Potassium borohydride is a selective reductant with wide solubility in protic media. Sodium tetrahydridoborate chemical compound britannica. Sodium borohydride revision date 17jan2018 attention is required.
A fine granular form of sodium borohydride available in 50kg drums. One reagent lane fair lawn, nj 07410 for information in north america, call. We include table showing common functional groups and their general reducibility by sodium borohydride, sodium borohydride. Sodium or potassium borohydride can also be used insitu to produce other more aggressive reducing agents cost effectively. Chemical product and company identification product name. Your new online msds binder is a place for you to store the material safety data sheets you need to deploy. Our products producers of sodium borohydride and other.
Sodium borohydride nabh4 is a mild reducing agent that is typically used to reduce aldehydes and ketones to their respective alcohols. Potassium borohydride an overview sciencedirect topics. Reduction of nitroarenes to azoxybenzenes by potassium. Sodium borohydride an overview sciencedirect topics. Do not store in glass containers, as pressure buildup could result in rupture and severe injury. The extent of sample preparation varies according to the method of detection. Sodium borohydride nabh4 high grade granular powder. Sodium borohydride nabh 4 was used as a reducing agent for coprecipitation of nanoparticles. Kemira sodium borohydride nabh4 an effective reducing agent. Eye contact rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes.
In the case of contact with eyes, rinse immediately with plenty of water and seek medical advice. University illinois urbana champaign urbana, illinois 61801 july 2627, 2005 by. It is decomposed by water to form sodium hydroxide, a corrosive material, and hydrogen, a flammable gas. Sigmaaldrich 3050 spruce street saint louis mo 63103 usa telephone. Sds of sodium borohydride, safety data sheets, cas 16940662. Sodium borohydride is a white to grayish crystalline powder. Firstaid measures general advice immediate medical attention is required. Sodium borohydride nabh4 determination, both qualitative and quantitative, is of great significance in a plethora of areas. Sodium borohydride sodium borohydride, also known as sodium tetrahydridoborate, has the chemical formula nabh4. Appendix 1 contains more information about the solubility of nabh 4. Sodium borohydride material safety data sheet name cas number.
Potassium borohydride is similar in properties and reactions to sodium borohydride, and. About sodium borohydride sodium hydroxide solution american elements manufactures highly stable aqueous solutions composed of 12% sodium borohydride and 40% sodium hydroxide for use as a. Contact of glycerol and sodium borohydride leads to ignition, other glycols and methanol are exothermic but do not ignite. The material itself is easily ignited and burns vigorously once ignited. Acros organics bvba janssen pharmaceuticalaan 3a 2440 geel. This white solid, usually encountered as a powder, is a specialty reducing agent used. Material safety data sheet sodium borohydride msds section 1. Properties of aqueous alkaline sodium borohydride solutions and byproducts formed during hydrolysis presented at the fuel cell design, fabrication and materials selection workshop grainger engineering library, room 335 1 w. Fire and explosion risk in contact with oxidizing agents. Potassium borohydride is a white, crystalline substance. Sodium borohydride is stored in a sealed container, away from moisture and water. Water, acid, or high temperatures can liberate flammable hydrogen gas. Sodium borohydride is the borohydride that is produced on the largest scale industrially, estimated at 5000 tonsy in 2002.
Potassium hydroxide can react with materials, such as acids, releasing enough. Properties of aqueous alkaline sodium borohydride solutions. About sodium borohydride sodium hydroxide solution american elements manufactures highly stable aqueous solutions composed of 12% sodium borohydride and 40% sodium hydroxide for use as a reducing agent in chemical manufacturing, metal catalyst recovery, water treatment, textile manufacturing, and other applications. If seeking medical attention, provide sds document to physician. Extremely hazardous in case of skin contact irritant, of eye contact irritant, of ingestion, of inhalation. Potassium borohydride un1870 dangerous when wet potassium borohydride. When handling sodium borohydride, nitrile or neoprene gloves, safety goggles and a flame retardant lab coat have to be worn. It converts aldehydes and ketones to the corresponding alcohols in the manufacture of. Incompatible materials strong oxidizing agents, aldehydes, ketones, acids, aluminium. Direct volumetric assay of sodium borohydride and potassium borohydride. Sodium hydride cas no 7646697 material safety data sheet sdsmsds.
As with other methods, they require the reduction of disulfide bonds and proteinbound homocysteine to free homocysteine. Tsuneo imamoto, in comprehensive organic synthesis, 1991. Immediately flush eyes with running water for at least 15 minutes, keeping eyelids open. The potassium form of borohydride is typically used in cases where sodium. Radchem cc po box 166982 brackendowns alberton 1454 telephone. Potassium borohydride kbh4 high grade granular powder. Eye contact rinse immediately with plenty of water, also under the eyelids, for at least 15. In our laboratory, sodium borohydride is used as a reducing agent and is prepared as aqueous or alcoholic solution. Borospec k powder 96% a powdered form of potassium borohydride available in 50kg drums. In contact with water releases flammable gases which may ignite spontan eously.
Nabh4 is sometimes used to reduce esters to alcohols but the reaction is generally slow. Metal recovery sodium borohydride is extremely effective in reducing metal ions back to their free metal state and is an economic way to remove metals such as silver, copper, and nickel from chelated wastewater streams. Sodium borohydride is an inorganic sodium salt and a metal tetrahydridoborate. These include nabh4 for energy systems such as direct borohydride fuel. Ac196550000, ac196550025, ac19655, ac196555000, ac418180000, ac41818 ac41818 synonyms. Nucleophilic addition of hydride ion from sodium borohydride is an inexpensive alternative method for the baylishillman reaction to form e. Common pyrophoric and waterreactive chemicals at mit. This is usually achieved with the use of dithioerythritol, sodium or potassium borohydride, and 2mercaptoethanol. This material contains potassium permanganate listed as manganese compounds, n.
The stability of sodium borohydride in organic solvents is dependent on the degree of hydrolysis that can occur. Laboratory chemicals gloucester house farnborough road farnborough united kingdom telephone uk. This white solid, usually encountered as a powder, is a reducing agent that finds application in chemistry, both in the laboratory and on an industrial scale. Separate determination of borohydride, borate, hydroxide, and carbonate in the borohydride fuel cell by acidbase and iodometric potentiometric titration. Do not use mouthtomouth method if victim ingested or inhaled the substance. Sodium borohydride, also known as sodium tetrahydridoborate and sodium tetrahydroborate, is an inorganic compound with the formula na bh 4. Your new online msds binder is a place for you to store the material safety data sheets. Sodium iodide, acs safety data sheet according to federal register vol. Sodium borohydride sodium hydroxide solution american.
Aluminum, tin, zinc, sodium borohydride, chlorine dioxide, nitrosomethylurea. Used extensively in organic reductions and applications not suitable with the liquid form. Reduction of nitroarenes to azoxybenzenes by potassium borohydride in water article pdf available in molecules 165. For the msds sds, please click on the pdf logo below opens in a new window. Ignition occurs if a mixture of the hydride and sulfuric acid is not cooled. Sodium hydride material safety data sheet cas no 7646697. Sigmaaldrich offers a number of sodium borohydride solution products. It is used in the manufacture of plastics, aldehydes, ketones, and acid chlorides. Hawleys condensed chemical dictionary, th edition,1997.
The ketodilactam 303, obtained as a byproduct in the oxidative rearrangement of 3oxotabersonine, was used in an investigation that clarified the behavior of vincatine 340 on reduction 217. Sodium borohydride revision date 17jan2018 stability water reactive. Safety data sheet northwest missouri state university. Sodium phosphate, dibasic, anhydrous safety data sheet according to federal register vol.
Combustion products may include carbon oxides or other toxic vapors. Potassium borohydride is a white crystalline or powdered solid. Sodium hydroxide behaves in a similar way as potassium hydroxide nsc newsletter, chem. Safety data sheet according to 29cfr19101200 and ghs rev. Other companies are charging thousands of dollars to set up accounts and give you access to their msds online database. Sodium borohydride is soluble in most polar solvents that contain a hydroxyl or an amine group. It is used as a hydrogen source and a foaming agent for rubbers.